周莉（教授）
研究方向：脂质组学等多组学新技术新方法及其在食药分析中的应用
1. 食品安全与真实性鉴别新技术新方法研究
2. AI赋能的天然活性物质挖掘及疾病防治新机制研究
电子邮箱：zhou2018@scuec.edu.cn
社会兼职：
现任九三学社湖北省省委委员、九三学社威尼斯886699支社主委
湖北省科技特派员、湖北省科技副总、湖北省“三区”科技人才、新疆阿拉山口海关技术中心特聘专家、湖北省“院士专家企业行”成员、江苏省“企业创新岗”特聘专家、江苏省科技副总
中国中药协会亚健康药物研究专委会常务委员、中国中药协会中药材检测认证技术专业委员会委员、湖北省药学会中药天然药专业委员会委员、湖北省植物学会委员
荣誉称号：
湖北省“楚天学者”人才计划；江苏省“双创博士”海外高层次人才
获奖情况：
湖北省科学技术奖（科技进步奖）二等奖（2022，排名第1）
中国民族医药学会科学技术奖二等奖（2024，排名第1）
中国民族医药协会科学技术进步二等奖（2024，排名第1）
湖北省侨联梁亮胜侨界科技奖励基金三等奖（2025，排名第1）
教育经历和工作简历：
2026.1-至今，威尼斯886699，药学院，教授
2018.4-2025.12，威尼斯886699，药学院，副教授
2013.9-2018.3，南京农业大学，食品科技学院，讲师，副教授
2009.10-2013.5，法国斯特拉斯堡大学，分析化学，博士
2002.9-2009.6，西南大学，食品科学，本科，硕士
科研项目：
1. 国家自然科学基金面上项目（No. 22578514），50万，项目负责人
2. 国家自然科学基金青年项目（No. 31501521），24万，项目负责人
3. 中央本级重大增减支项目（No. 2060302）, 20万，项目负责人
4. 湖北省自然科学基金面上项目（No. 2022CFB458）, 5万，项目负责人
5. 江苏省自然科学基金青年项目（No. BK20140701），20万，项目负责人
6. 第48批教育部留学人员回国科技基金，3万，项目负责人
7. 武汉市自然科学探索计划（No. 2025040601020161）, 10万，项目负责人
8. 国家重点研发计划，“中医药现代化”重点专项（No. 2020YFC1712702），2584万，骨干成员
9. 国家重点研发计划，食品营养与安全关键技术研发重点专项（No. 2023YFF1104002），95万，骨干成员
10. 国家自然科学基金面上项目（No. 31972164），58万，骨干成员
国际交流合作项目：
1. 国家科技部高端外国专家计划，《质谱技术在慢性代谢疾病早期预防和调控中的应用》（No. G2023185002L），30 万，项目负责人
2. 国家科技部高端外国专家计划，《质谱技术在药物分析中的开发与应用》（No. G2021185011L），10万，项目负责人
教学与培养学生：
主讲本科生课程，包括《医药数理统计》、《药物分析》、《药学类专业英语》等理论课程教学，《药物分析实验》、《药物色谱分析实践》等实验实践课程教学，以及《走进法国-饮食文化鉴赏》公选课。研究生课程《高等中药分析学》。
主持省级、校级教改项目4项，发表国家级和省级核心教研论文6篇。荣获威尼斯886699五四青年（教工）先锋，威尼斯886699研究生创新基金优秀指导老师、 “挑战杯”大学生课外学术科技作品竞赛优秀指导老师、第四届威尼斯886699科普讲解大赛三等奖、威尼斯886699优秀学士学位论文指导老师、威尼斯886699优秀教职工。指导学生获得研究生国家奖学金、威尼斯886699优秀研究生标兵或优秀研究生、研究生创新基金成果展一等奖等一系列荣誉。
授权专利：
1. 周莉，杨富. 一种基于脂质组学的真菌的鉴别方法. 中国发明专利，ZL202110975298.8
2. 周莉，朱津瑞、杨富. 一种从牛肝菌中提取分离甜菜碱脂的方法. 中国发明专利，ZL202111061854.7
3. 周莉，张明浩，刘吉开. 一种蛋白质为关键的南极磷虾油可食用产品. 中国发明专利，ZL202110155040.3
4. 周莉，李享，张明浩，刘吉开. 一种负载辅酶Q10的高内相皮克林乳剂及其制备方法. 中国发明专利，ZL202211255321.7
5. 周莉，曾晓雄. 一种羧甲基壳聚糖包覆的南极磷虾油纳米脂质体及其制备方法. 中国发明专利，ZL201710338465.1
6. 周莉，张明浩，陈孝武. 一种由山茶油和茶枯饼提取物制备的高内相Pickering乳液. 中国发明专利，ZL202111071888.4
7. 周莉，胡玥琦，陈孝武，刘吉开. 一种从山茶油副产物油枯饼中提取山奈酚的方法. 中国发明专利，ZL202211042140.6
8. 周莉，李享，张明浩，刘吉开. 一种从竹荪中提取分离蛋白质的方法. 中国发明专利，ZL202111519465.4
代表性论文（第一作者或通讯作者）：
1. Liu Yi, Zhu Jinrui, Zhao Minjie, Marchioni Eric, Zhou Li*, Fu Haiyan*. Lipidomics-based authentication of Tricholoma matsutake by UHPLC-HR-MS/MS combined with chemometrics. Journal of Food Composition and Analysis, 2026, 149, 108702.
2. Zhou Li#, Ma Yue#, Xu Junjie, Hu Yueqi, Zhao Minjie, Marchioni Eric, Fu Haiyan*. Determination and comparison of lipid profiles of Chinese green tea varieties using untargeted lipidomics analysis combined with chemometrics. Food Chemistry, 2025, 477, 143467.
3. Yao Jiaxu, Zhu Jinrui, Marchoni Eric, Zhao Minjie, Li Haijiao*, Zhou Li*. Discrimination of wild edible and poisonous fungi with similar appearance (Cantharellus albovenosus vs Omphalotus olearius) based on lipidomics using UHPLC-HR-AM/MS/MS. Food Chemistry, 2025, 466, 142189.
4. Huang Rong, Zhang Wenyu, Hu Yueqi, Xu Junjie, Dong Zhihui, Liu Jikai*, Zhou Li*. Houttuynia cordata polysaccharides ameliorate atopic dermatitis in mice through modulation of skin immune barrier and lipid metabolism. International Journal of Biological Macromolecules, 2025, 314, 144264.
5. Suo Yixin, Zhou Li*, Long Wanjun, Marchioni Eric Zhao Minjie, Fu Haiyan*, She Yuanbin*. Novel colorimetric sensor based on aggregation of noble metal nanomaterials for authenticity identification of Lycium ruthenicum from different regions. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126295.
6. Ma Yue, Zhu Jinrui, Liu Yi, Feng Yi, Xiang Dingkui, Marchioni Eric, Zhao Minjie, Zhou Li*, Fu Haiyan*. Identification of wolfberry origins using lipidomics and chemometric analysis. Journal of Food Composition and Analysis, 2025, 146, 107946.
7. Xiang Dingkui, Liu Yi, Zhao Minjie, Ma Yue, Marchioni Eric, Chen Heping*, Zhou Li*. Discrimination of Russula vinosa Lindblad from different origins by lipidomics analysis using UHPLC-HR-AM/MS/MS. Journal of Food Composition and Analysis, 2025, 148, 108387.
8. Suo Yixin, Long Wanjun, Qi Linlin, Yao Fangmi, Lei Guanghua, Guang Yuting, Hu Zikang, Marchioni Eric, Zhao Minjie, Zhou Li*, Fu Haiyan*. Fluorescent sensor based on CdTe-QDs @ N-CDs complexes for visual identification of goji berries origin. Sensors and Actuators B-Chemical, 2024, 406, 135438.
9. Hu Yueqi, Zhou Li, Yang Jian, Bai Ruibin, Marchioni Eric, Zhao Minjie, Zhou Li*. Anti-inflammatory mechanism of Houttuynia cordata polysaccharides against ulcerative colitis based on multi-omics conjoint analysis. International Journal of Biological Macromolecules, 2024, 283, 137311.
10. Song Ankang, Li Yaobo, Wang Wei, Hu Yueqi, Xu Junjie, Xu Zhixin, Zhou Li*, Liu Jikai*. Revealing the effect of sea buckthron oil, fish oil and structured lipid on intestinal microbiota, colonic short chain fatty acid composition and serum lipid profiles in vivo. Natural Products and Bioprospecting, 2024, 14, 41.
11. Hu Yueqi, Suo Yixin, Ma Yue, Marchioni Eric, Zhou Li*, Liu Jikai*. Differentiation of lipid profiles of hen eggs from different regions based on lipidomics combined with chemometrics. Journal of Food Composition and Analysis, 2024, 130, 106153.
12. Hu Yueqi, Wu Xin, Zhou Li*, Liu Jikai*. Which is the optimal choice for neonates’ formula or breast milk? Natural Products and Bioprospecting, 2024, 14, 21.
13. Zhu Jinrui, Zhou Li*, Zhao Minjie, Wei Fang*, Fu Haiyan*, Marchioni Eric. Revealing the dynamic changes of lipids in coffee during roasting based on UHPLC-QE-HR-AM/MS/MS. Food Research International, 2023, 174, 113507.
14. Ma Yue, Yao Jiaxu, Zhou Li*, Zhao Minjie, Wang Wei, Liu Jikai*, Marchioni Eric. Comprehensive untargeted lipidomic analysis of sea buckthorn using UHPLC-HR-AM/MS/MS combined with principal component analysis. Food Chemistry, 2024, 430, 136964.
15. Yao Jiaxu, Zhou Li*, Hu Yueqi, Zhao Minjie, Ma Yue, Liu Jikai*, Marchioni Eric. Combining untargeted lipidomics analysis and chemometrics to identify the edible and poisonous mushrooms (Pleurotus cornucopoiae vs Omphalotus japonicus). Journal of Agricultural and Food Chemistry, 2023, 71, 8220-8229. (Front Cover)
16. Li Xiang, Zhang Minghao, Zhou Li*, Liu Jikai*, Marchioni Eric. Construction of whey protein gels prepared by three methods to stabilize high internal phase Pickering emulsions loaded with CoQ10 under different pH. Food Chemistry, 2023, 421, 136192.
17. Ma Yue, Yao Jiaxu, Zhou Li*, Zhao Minji, Liu Jikai*, Marchioni Eric. Characterization and discrimination of volatile organic compounds and lipid profiles of truffles under different treatments by UHPLC-QE Orbitrap/MS/MS and P&T-GC-MS. Food Chemistry, 2023, 410, 135432.
18. Zhou Li, Guan Yuting, Yao Jiaxu, Zhao Minjie, Fu Haiyan, Liu Jikai*, Marchioni Eric. Identification and discrimination of lilii bulbus origins based on lipidomics using UHPLC-QE-Orbitrap/MS/MS combined with chemometrics analysis. Journal of Food Composition and Analysis, 2023, 123, 105512.
19. Zhang Minghao, Li Xiang, Zhou Li*, Chen Weilin, Marchioni Eric. Protein-Based High Internal Phase Pickering Emulsions: A Review of Their Fabrication, Composition and Future Perspectives in the Food Industry. Foods, 2023, 12, 482.
20. Yao Jiaxu, Zhu Jinrui, Zhao Minjie, Zhou Li*, Marchioni Eric. Untargeted lipidomics method for the discrimination of five crab Species by ultra-high-performance liquid chromatography high-resolution mass spectrometry combined with chemometrics. Molecules. 2023, 28, 3653.
21. Zhu Jinrui, Zhou Li*, Yao Jiaxu, Hu Yueqi, Li Zhenghui, Liu Jikai*, Marchioni Eric. Untargeted metabolomics analysis combined with chemometrics reveals the effects of different cooking methods on Lentinus edodes. Molecules, 2023, 28(16), 6009.
22. Rong Huang, Jiaxu Yao, Zhou Li*, Xiang Li, Jinrui Zhu, Yueqi Hu, Jikai Liu*. Protective effect and mechanism insight of purified Antarctic kill phospholipids against mice ulcerative colitis combined with bioinformatics. Natural Products and Bioprospecting. 2023, 5, 13(1),14.
23. Zhang Minghao, Zhu Jinrui, Zhou Li*, Kan Jianquan, Zhao Minjie, Huang Rong, Liu Jikai*, Marchioni, Eric. Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo. Journal of Functional Foods, 2022, 94, 105134.
24. Zhou Li*, Ma Yue, Yao Jiaxu, Zhang Minghao, Fu Haiyan*, Yang Jian, Liu Jikai*, Zhao Minjie, Marchioni Eric. Discrimination of chrysanthemum varieties using lipidomics based on UHPLC-HR-AM/MS/MS. Journal of the Science of Food and Agriculture, 2022, 103, 837-845. (Front Cover)
25. Zhang Minghao, Zhao Naiyu, Xie Minhao, Dong Deqiao, Chen Weilin, He, Yuanpeng, Yan Dalin, Fu Haiyan, Liang Xinlin, Zhou Li*. Antioxidant properties of polyphenols from snow chrysanthemum (Coreopsis tinctoria) and the modulation on intestinal microflora in vitro. Pharmaceutical Biology, 2022, 60, 1771-1780.
26. Zhang Minghao, Zhou Li*, Yang Fu, Yao Jiaxu, Ma Yue, Liu Jikai*. Construction of high internal phase Pickering emulsions stabilized by bamboo fungus protein gels with the effect of pH. Food Chemistry, 2022, 369, 130954.
27. Yang Fu, Zhao Minjie, Zhou Li*, Zhang Minghao, Liu Jikai*, Marchioni Eric. Identification and differentiation of wild edible mushrooms based on lipidomics profiling combined with principal component analysis. Journal Agricultural and Food Chemistry, 2021, 69, 9991-10001. (Front Cover)
28. Zhou Li*, Yang Fu, Zhao Minjie, Liu Jikai*, Marchioni Eric. Determination and comparison of phospholipid profiles in eggs from seven different species using UHPLC-ESI-Triple TOF-MS. Food Chemistry, 2021, 339, 127856.
29. Zhou Li，Wu Xing, Yang Fu, Zhang Minghao, Huang Rong*, Liu Jikai*. Characterization of molecular species and anti-inflammatory activity of purified phospholipids from Antarctic krill oil. Marine Drugs, 2021, 19, 124.
30. Zhou Li*，Yang Fu, Zhang Minhao, Liu Jikai*. A green enzymatic extraction optimization and oxidative stability of krill oil from Euphausia Superba. Marine Drugs, 2020, 18(2), 82.
31. Zhou Li, Xie Minhao, Yang Fu, Liu Jikai*. Antioxidant activity of high purity blueberry anthocyanins and the effects on human intestinal microbiota. LWT- Food Science and Technology, 2020, 117, 108621. (Highly Cited Paper)
32. Yang Fu, Zhou Li*, Zhang Minhao, Liu Jikai*, Marchioni Eric. Exploration of natural phosphatidylcholine sources from six beans by UHPLC-Q-HRMS. Journal of Food Science, 2020, 85(10), 3202-3213.
33. Zhou Li*, Wang Yan, Wang Xiaolin, Liang Yi, Huang Zheng. Determination of phosphatidylcholine in shrimps by high resolution mass spectrometry. Analytical Letters, 2019, 52, 308-319.
34. Zhou Li, Wang Yan, Wang Xiaolin, Liang Yi, Huang Zheng, Zeng Xiaoxiong*. MALDI-TOF/TOF mass spectrometric determination and antioxidative activity of purified phosphatidylcholine fractions from shrimp species. Journal of Agricultural and Food Chemistry, 2017, 65, 1229-1238.
35. Zhou Li, Li Peixuan, Zhao Yuling, Hou Shuang, Cong Baolei, Huang Jun, Ding Yu, Zeng Xiaoxiong*. Optimization of lipid extraction and determination of fatty acid compositions in edible meats of freshwater and marine shrimps. Journal of Aquatic Food Product Technology, 2017, 26, 824-834.
36. Zhou Li, Wang Wei, Huang Jun, Ding Yu, Pan Zhouqiang, Zhao Ya, Zhang Renkang, Hu Bing, Zeng Xiaoxiong*. In vitro extraction and fermentation of polyphenols from grape seeds (Vitisvinifera) by human intestinal microbiota. Food & Function, 2016, 7, 1959-1967.
37. Zhou Li*, Zhao Minjie, Ennahar Saïd, Bindler Françoise, Marchioni Eric. Identification of oxidation compounds of 1-stearoyl-2- linoleoyl-sn-glycero-3-phosphoethanolamine during thermal oxidation. Journal of Agricultural and Food Chemistry, 2015, 63(43), 9615-9620.
38. Zhou Li*, Zhao Minjie, Bindler Françoise, Marchioni Eric. Comparison of the volatiles formed by oxidation of phosphatidylcholine to triglyceride in model systems. Journal of Agricultural and Food Chemistry, 2014, 62, 8295-8301.
39. Zhou Li, Zhao Minjie, Khalil Ali, Marcic Christophe, Bindler Françoise, Marchioni Eric*. Identification of volatiles from oxidised phosphatidylcholine molecular species using headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS). Analytical and Bioanalytical Chemistry, 2013, 405, 9125-9137.
40. Zhou Li, Khalil Ali, Bindler Françoise, Zhao Minjie, Marcic Christophe, Ennahar Saïd, Marchioni Eric*. Effect of heat treatment on the content of individual phospholipids in coffee beans. Food Chemistry, 2013, 141, 3846-3850.
41. Zhou Li, Zhao Minjie, Ennahar Saïd, Bindler Françoise, Marchioni Eric*. Determination of phosphatidylethanolamine molecular species in various food matrices by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS2). Analytical and Bioanalytical Chemistry, 2012, 403(1), 291-300.
42. Zhou Li, Zhao Minjie, Ennahar Saïd, Bindler Françoise, Marchioni Eric*. Liquid chromatography-tandem mass spectrometry for the determination of sphingomyelin species from calf brain, ox liver, egg yolk, and krill oil. Journal of Agricultural and Food Chemistry, 2012, 60(1), 293-298.
43. Zhou Li, Le Grandois Julie, Marchioni Eric*, Zhao Minjie, Ennahar Saïd, Bindler Françoise. Improvement of total lipid and glycerophospholipid recoveries from various food matrices using pressurized liquid extraction. Journal of Agricultural and Food Chemistry, 2010, 58, 9912-9917.
